The recordings of the Sam Gyson Show consist of political commentary, local news, and interviews. The interviewees include national and local politicians, legal and medical professionals, journalists, as well as entertainers and sports personalities. Most of the shows were broadcast from WMBM and WAXY-AM radio stations in Miami between 1988 and 2001.

The bulk of the collection consists of 256 audio cassette tapes that span 1950 to 2001. The first tape in the collection is a show recorded in 1950 with Gyson, Phil Ramone, Ben Kelly, and Harry Martin. The second tape in the collection is an interview with Larry King from 1976.

The majority of the tapes in the collection span from 1997–1999. There are no tapes in the collection from the years 1989 or 1995.The last 10 tapes in the collection are miscellaneous shows that could not be dated, yet the guests have been identified.

One folder contains of articles, letters, memos, awards, photographs, and an 18-page draft of a prospectus for an autobiography by Gyson called, Short Takes and Some Mistakes.